Thursday, January 5, 2012

Texas police kill 8th-grader carrying pellet gun (AP)

BROWNSVILLE, Texas ? Police shot and killed an eighth-grader in the hallway of his middle school Wednesday after the boy brandished what looked like a handgun and pointed it at officers. It turned out to be a pellet gun that closely resembled the real thing.

Fifteen-year-old Jaime Gonzalez "had plenty of opportunities to lower the gun and listen to the officers' orders, and he didn't want to," Interim Police Chief Orlando Rodriguez said.

Shortly before the confrontation, the boy had walked into a classroom and punched a random boy in the nose for no apparent reason, police said. Investigators did not know why he pulled out the weapon.

"We think it looks like this was a way to bring attention to himself," the police chief said. He said the officers' actions were justified and no one else was hurt.

Authorities declined to share what the boy said before being shot.

The shooting happened during first period at Cummings Middle School in Brownsville. Teachers locked classroom doors and turned off lights, and some frightened students dove under their desks. They could hear police charge down the hallway and shout for Gonzalez to drop the weapon, followed by several shots.

Two officers fired three shots, hitting Gonzalez at least twice, police said.

The boy's father, Jaime Gonzalez Sr., said he had no idea where his son got the gun or why he brought it to school.

"We wouldn't give him a gift like that," he told The Associated Press from the family's home, where other relatives and friends of his son were gathering Wednesday night.

He said nothing seemed amiss when he, his wife and their son went out for nachos the night before, then went home and watched a movie. He said he last saw his son Wednesday morning, when the boy said goodbye before leaving to catch the bus to school.

Gonzalez Sr. was struggling to reconcile the day's events, saying his son seemed to be doing better in school and was always helpful around the neighborhood mowing neighbors' lawns, washing dogs and carrying his toolbox off to fix other kids' bikes.

Both he and his wife, Noralva, questioned why police repeatedly shot at their son and called the shooting unjustified.

"Why was so much excess force used on a minor?" he asked. "Three shots. Why not one that would bring him down?"

His wife, who demanded that the officers be punished, added: "What happened was an injustice."

Rodriguez said his officers "took the necessary action to protect themselves and the other kids." There weren't many others in the hall at the time, but "they had every right to take the action that they took."

The boy's godmother, Norma Leticia Navarro, said she couldn't imagine why he would have brought a gun to school.

"I wish I could ask him why he did that, `Why did you put yourself in that position?'"

She said she understood that police were doing their job, but she wondered if other steps could have been taken.

"Jaime was not a bad kid," she said. "I'm not saying he was perfect or an angel, but he was a very giving person."

David A. Dusenbury, a retired deputy police chief in Long Beach, Calif., who now consults on police tactics, said the officers were probably justified in their actions.

If the boy was raising the gun as if to fire at someone, "then it's unfortunate, but the officer certainly would have the right under the law to use deadly force."

Administrators said the school would be closed Thursday but that students could attend classes at a nearby elementary school if they wished.

Superintendent Carl Montoya remembered Gonzalez as "a very positive young man."

"He did music. He worked well with everybody. Just something unfortunately happened today that caused his behavior to go the way it went. So I don't know."

Gina Rangel was in her first-period class in the gym when the school was locked down. She said friends who were closer to the confrontation heard the boy threaten to kill everyone.

Her mother, Irma Rangel, said she was worried about the school's safety "because if this happened once, kids imitate."

Brownsville, on Texas' southern tip, is beset by spillover violence from Mexico's drug war. As word of the shooting spread through the city, frantic parents rushed to reach their children.

Those who got there early were able to retrieve their kids, but some who arrived later found the street outside the school lined with squad cars and blocked off.

Two hours later, dozens of frustrated parents and relatives flooded out of the park pavilion without their children after school officials announced that all remaining children had been bused to a high school and could be picked up there.

Julie Tomalenas waited for an hour to pick up her 13-year-old sister before being told of the relocation.

"It was very stressful not knowing if she was OK, where she was, when we could see her again," she said.

Wednesday night, two dozen friends and classmates gathered in the dark street outside the family's home. Jaime's best friend, 16-year-old Star Rodriguez, said her favorite memory was when Jaime came to her party Dec. 29 and they danced and sang together.

"He was like a brother to me," she said.

___

Associated Press writers Diana Heidgerd and Danny Robbins in Dallas and Mike Graczyk in Houston contributed to this story.

Source: http://us.rd.yahoo.com/dailynews/rss/topstories/*http%3A//news.yahoo.com/s/ap/20120105/ap_on_re_us/us_texas_student_shot

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Wednesday, January 4, 2012

A positive feedback signaling loop between ATM and the vitamin D receptor is critical for cancer chemoprevention by vitamin D.

Abstract

Both epidemiological and laboratory studies have demonstrated the chemopreventive effects of 1-alpha,25- dihydroxyvitamin D3 (1,25-VD) in tumorigenesis. However, understanding remains incomplete concenrning the molecular mechanism by which 1,25-VD prevents tumorigenesis. In this study, we used an established mouse model of chemical carcinogenesis to investigate how 1,25-VD prevents malignant transformation. In this model, 1,25-VD promoted expression of the DNA repair genes RAD50 and ATM, both of which are critical for mediating the signaling responses to DNA damage. Correspondingly, 1,25-VD protected cells from genotoxic stress and growth inhibition by promoting double strand break DNA repair. Depletion of the vitamin D receptor (VDR) reduced these genoprotective effects and drove malignant transformation that could not be prevented by 1,25-VD, defining an essential role for VDR in mediating the anti-cancer effects of 1,25-VD. Notably, genotoxic stress activated ATM and VDR through phosphorylation of VDR. Mutations in VDR at putative ATM phosphorylation sites impaired the ability of ATM to enhance VDR transactivation activity, diminishing 1,25- VD-mediated induction of ATM and RAD50 expression. Together, our findings identify a novel vitamin D-mediated chemopreventive mechanism involving a positive feedback loop between the DNA repair proteins ATM and VDR.

Source: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?tmpl=NoSidebarfile&db=PubMed&cmd=Retrieve&list_uids=22207345&dopt=Abstract

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Tuesday, January 3, 2012

holgr: RT @csoghoian: My first experiment with a micro-targeted ad campaign. Paying Facebook $20 to ask Twitter employees to stop logging IPs h ...

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My first experiment with a micro-targeted ad campaign. Paying Facebook $20 to ask Twitter employees to stop logging IPs i.imgur.com/6DvaH.png csoghoian

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NBA: Los Kings ganan derrotan a los Hornets 96-80

Publicado: 2 ene. 2012 7:48 AM

SACRAMENTO, ene. 2 (UPI) -- Los Kings de Sacramento doblegaron por 96-80 sobre los Hornets de New Orle?ns de la mano de Tyreke Evans, quien sum? 27 puntos unidades.

Por su parte Marcus Thornton contribuy? con 25 unidades para el local.

Igualmente por los Kings el quisqueyano Francisco Garc?a estuvo en cancha 9:23 minutos encestando dos de sus cuatro intentos y tuvo dos rebotes.

Para New Orle?ns que ha perdido dos encuentros al hilo, Tervor Ariza sum? 17 puntos, Chris Kaman contribuy? con 14 puntos y 15 rebotes, en tanto Emeka Okafor tuvo 13 puntos y 12 rebotes.

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Source: http://espanol.upi.com/Deportes/2012/01/02/NBA-Los-Kings-ganan-derrotan-a-los-Hornets-96-80/UPI-87631325501296/

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Monday, January 2, 2012

TopBDNews: Crowd fights Chinese police at mosque demolition; 80 detained - http://t.co/FbviTsDe: A crowd of Muslims fought... http://t.co/JIC2W7mX

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Source: http://twitter.com/TopBDNews/statuses/153764190744608769

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Obama hopeful for progress in 2012 (AP)

HONOLULU ? President Barack Obama says Congress' eventual willingness to come together and prevent year-end tax increases makes him hopeful of more economic progress to come in 2012.

"It was good to see members of Congress do the right thing for millions of working Americans," said Obama, using his weekly radio and Internet address to deliver a New Year's message.

In Saturday's address, the president said a key reason lawmakers eventually forged an agreement to extend a Social Security payroll tax cut for two more months was the input from the public. Through phone calls, email and Twitter, Obama said, the American people "had the courage to believe your voices could make a difference."

The president said he expects Congress to finish the job when lawmakers return to Washington in January and extend the payroll tax cuts through the end of the year.

Reflecting on 2011, Obama said it was a time of great challenge and great progress for the U.S., including the end of the war in Iraq, the death of Osama bin Laden and signs of an economic recovery.

"There's no doubt that 2012 will bring even more change," Obama said. "And as we head into the new year, I'm hopeful that we have what it takes to face that change and come out even stronger ? to grow our economy, create more jobs and strengthen the middle class."

On the eve of an election year, Obama said the months ahead will help determine "what kind of country we want to be and what kind of world we want our children and grandchildren to grow up in."

Georgia Republican Sen. Johnny Isakson, delivering the GOP address, outlined his party's commitments to the American people for 2012.

Isakson said the party's No. 1 goal is to make it easier for small businesses to create jobs.

"We'll accomplish this by focusing on three things: fundamental tax reform, regulatory reform and energy security," he said.

Isakson said that while some people may think Congress will be too consumed with the 2012 elections to accomplish anything significant, the public deserves better.

"Americans cannot wait until after the November election," he said. "They need us to do our job and do it right now to create an economic climate that makes it easier to put people back to work."

___

Online:

Obama address: www.whitehouse.gov

GOP address: http://www.youtube.com/gopweeklyaddress

Source: http://us.rd.yahoo.com/dailynews/rss/obama/*http%3A//news.yahoo.com/s/ap/20111231/ap_on_go_pr_wh/us_obama

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Sunday, January 1, 2012

Air India finally coming of age

Air India finally coming of age

Air India, by raising its capital by Rs. 7500 crores will not only perform better but will also save an amount of Rs 1000 crore, which they are paying as an interest to their bankers annually.

DURING NOVEMBER 2011 they have picked up a reasonable good business with an increase of 12.3 % in Aviation Grid while for the same period there has been an increase of 10 % in the number of Passengers carried; good going indeed.


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The Air India Management in their Committee Meeting held recently, decided to issue Preferential Shares amounting to Rs 7500 Crores to their Bankers. There are 21 Banks with whom Air India has their official link.


Being a State owned carrier, a formal approval from the Ministry of Civil Aviation, Govt of India is a must which may take its own time. We know very well how our system works.

Meanwhile Air India Board has appointed a four-member panel to finalize the selection of the Chief Operating Officers for Air India and its low cost subsidiary named Air India Express. The applications are already pouring in and the interviews are likely to take place very?? shortly.

Air India thus by raising its capital by 7500 crores will not only perform better but will also save an amount of Rs 1000 crore which they are paying as interest to their bankers annually.


The Management of the State Bank of India has already taken a lead by processing their requests to the Reserve Bank of India for its occurrence. Probably they want to acquire good percentage of their share in Air India?s total working capital. Indeed a good business step for any Banker.

We wish all the best to the Air India Management to come out with a grand success in the process which they should have thought long ago.

?

Source: http://www.merinews.com/article/air-india-finally-coming-of-age/15863358.shtml

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